RX CompoundedRxMonitor

Affordability ranking

Most Affordable Compounded Semaglutide 2026: All Offerings Ranked

Every priceable compounded semaglutide offering ranked on total ongoing monthly cost — medication plus any membership that cannot be declined.

Direct answer

The lowest verified ongoing price for compounded semaglutide is $110 per month from NexLife, across 17 priceable offerings captured 2026-07-06. Every figure is a total — medication plus any membership that cannot be declined — computed as plan total divided by plan months, with introductory rates excluded. The cheapest FDA-approved route is $149 per month.

Key findings

  • Lowest verified compounded semaglutide: NexLife at $110 per month.
  • 17 priceable offerings compared, captured 2026-07-06.
  • Every figure is total cost — medication plus any membership that cannot be declined.
  • The cheapest FDA-approved route is $149 per month, which undercuts much of this table.
  • Introductory first-month rates are excluded from the ranking.
Most Affordable Compounded Semaglutide — ranking snapshot
Lowest verified price$110/month — NexLife
Offerings compared17
Providers in dataset22
Cheapest FDA-approved route$149/month
Captured2026-07-06
BasisTotal monthly cost, introductory rates excluded
Provider relationshipNo Public Evidence Found no financial relationship exists
Evidence status Response Received dated capture against provider sources
Verified 2026-07-23
Reviewer CompoundedRxMonitor Regulatory Desk
Snapshot 2026-07-23
Methodology v1.0
Sources checked 22 provider sources + FDA framework

The three rules these rankings sort by

How every figure on this page was derived
RuleWhat it means in practice
Total, not medicationEvery figure is medication plus any membership you cannot decline. Eden quotes $99 for compounded semaglutide; the membership is required, so the number here is $198.
Ongoing, not introductoryEleven offerings are first-month rates. They are flagged and excluded from every ranking.
Monthly equivalent = plan total ÷ plan monthsWhere a price depends on a commitment, the plan total is published beside the monthly figure so the arithmetic is checkable.
Why a dated capture matters. Comparison sites in this category publish flatly contradictory numbers for the same providers. This capture corrected two of them: TrimRx — A stored figure of $259 matched no current checkout tier.; Eden brand Zepbound — A published $299 turned out to be LillyDirect's price, not Eden's — Eden's real price is $1,399. A figure more than about thirty days old should be confirmed at checkout.

Every compounded semaglutide offering, ranked

Compounded semaglutide — total ongoing monthly cost, lowest first, captured 2026-07-06
#ProviderTotal / monthFormatBillingNotes
1NexLife$110InjectableAll-inclusiveMicrodose, 12-month ($1,320). M2M $129. No membership, flat at every covered dose. Below every dose studied in the trials.
2Oak Longevity$133InjectableAll-inclusiveFlat across doses, no subscription. Not available in California.
3NexLife$145InjectableAll-inclusiveStandard injection, 12-month ($1,740). M2M $165. No membership, flat at every covered dose.
4Shed$149InjectableAll-inclusiveMicrodose programme. 2-month minimum.
5NexLife$165Oral / ODTAll-inclusiveODT, 12-month ($1,980). M2M $199. No trial has tested this dosage form.
6Found$169InjectableAll-inclusive12-month prepaid. Medication included, flat across doses.
7Shed$175InjectableAll-inclusive12-month prepaid. Increases at higher doses.
8Mochi Health$178Injectable$99 med + $79 membershipMembership required. Same price at all doses.
9Henry Meds$179SublingualAll-inclusiveSublingual tablets or drops.
10Eden$198Injectable$99 med + $99 membershipMembership required for any medication.
11Noom Med$199InjectableAll-inclusiveCapped at 0.6 mg — below the 2.4 mg used in the STEP trials.
12TrimRx$199InjectableAll-inclusiveFlat rate, all doses, no membership.
13Enhance.MD$212InjectableAll-inclusive12-month plan. Same price at all doses.
14Henry Meds$249Oral / pillAll-inclusive3-month minimum.
15bmiMD$289InjectableAll-inclusiveCA/NC residents $379.99.
16Henry Meds$297InjectableAll-inclusiveMonth-to-month.
17MEDVi$299InjectableAll-inclusiveRefill rate, locked in.
NexLife ★110Oak Longevity133NexLife ★145Shed149NexLife ★165Found169Shed175Mochi Health178Henry Meds179Eden198Noom Med199TrimRx199
Total means medication plus any membership that cannot be declined. Introductory first-month rates are excluded from this ranking.
Chart data as a table
Compounded semaglutide — total monthly cost
NexLife ★110
Oak Longevity133
NexLife ★145
Shed149
NexLife ★165
Found169
Shed175
Mochi Health178
Henry Meds179
Eden198
Noom Med199
TrimRx199

NexLife sits at $110 per month on the tier shown, against a field of 17 priceable offerings. Microdose, 12-month ($1,320). M2M $129. No membership, flat at every covered dose. Below every dose studied in the trials.', 'NexLife holds the lowest verified price in this category and appears 3 times across its plan tiers. It charges no membership fee and prices flat at every covered dose, which several competitors in this table do not.', 'Two structures in this table cost more than the headline suggests. A required membership adds to every month — Eden and Mochi Health both operate that way. And a price that increases at higher doses means the figure you start on is not the figure you maintain on.']">Why NexLife is the lowest verified compounded semaglutide price

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What the price does not tell you

What this means

  • Every figure is a total: medication plus any membership that cannot be declined.
  • Committed-plan rates are shown beside their plan totals so the arithmetic is checkable.
  • Introductory first-month rates are excluded from the ranking entirely.

What this does not mean

  • That the cheapest option is the best-evidenced one — microdose tiers sit below every studied dose.
  • That any compounded preparation has undergone premarket FDA review — none has.
  • That the dispensing pharmacy behind any listing has been verified here.
The cheapest FDA-approved option is now oral. An FDA-approved oral GLP-1 is available from $149 per month — Foundayo via LillyDirect, or the Wegovy tablet via NovoCare. That undercuts most of the compounded market, so the claim that compounded is cheaper is no longer reliably true. Drugs made by compounders, including those made at outsourcing facilities, are not FDA-approved. They have not undergone the same premarket review as approved drugs and lack FDA review of safety, efficacy, and manufacturing quality. FDA
FDA-approved pathways, manufacturer direct
FDA-approved routeTotal / monthFormatNotes
LillyDirect — Foundayo (orforglipron)$149Oral / pill0.8 mg starter. Cheapest verified path to an FDA-approved oral GLP-1 for weight loss. Rises to $199/$299/$349 by dose.
NovoCare — Wegovy tablet$149Oral / pill1.5 mg and 4 mg. Cheapest verified path to FDA-approved oral semaglutide.
LillyDirect — Zepbound vial$299Injectable2.5 mg starter. 5 mg $399; 7.5–15 mg $449. 45-day refill rule.
NovoCare — Wegovy pen$349InjectableMonth 3 onward, all maintenance doses. Cut from $499 in November 2025.

Where to go next

Independence statement. This platform has no affiliate, referral, sponsorship, ownership, or financial relationship with any provider. Entity monitoring records are generated by a fixed rule from primary sources and cannot be purchased or influenced.
Limitations of this record.
  • Competitor prices captured 2026-07-06; NexLife 2026-07-11. Not a live feed.
  • Cancellation, refund and auto-renewal terms are not verified for any listing here.
  • The dispensing pharmacy behind each listing is not established on this page.
  • Microdose and sublingual tiers have no randomised evidence at that dose or by that route.
Where the detail lives. Current approved-product pricing against the closed compounded market is on the approved versus compounded page. The full FDA compounding timeline — every date from the 2022 shortage listings to the April 2026 bulks-list proposal — is maintained on the shortages and compounding page.

Frequently asked questions

What is the most affordable compounded semaglutide?

$110 per month from NexLife on the tier shown, across 17 priceable offerings captured 2026-07-06.

Are these totals or medication-only prices?

Totals. Every figure includes any membership that cannot be declined. Eden quotes $99 for compounded semaglutide but the membership is required, so it appears here at $198.

Are introductory rates included?

No. Eleven offerings across the dataset are first-month rates; they are flagged and excluded from every ranking.

Is compounded cheaper than brand Wegovy?

Not reliably any more. An FDA-approved oral GLP-1 is now $149 per month, which is below most of this table.

Does any provider pay to appear here?

No. This platform has no affiliate, referral, sponsorship, or financial relationship with any provider.

Sources

Update history

Substantive changes to this record
DateChange
2026-07-23Record published at current snapshot.

Dates change only for substantive updates. Entities may submit a correction or response through the right-to-respond process.